Author

S. I. Goldstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Emili· 3 shared A. B. Balazs· 1 shared A. C. Fan· 1 shared A. J. Trachtenberg· 1 shared A. K. O'Connell· 1 shared A. Klose· 1 shared A. L. Wong· 1 shared A. Ploss· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBiochemistry

A. Emili

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays

S. I. Goldstein, A. C. Fan, Z. Wang, S. K. Naineni, S. B. Garcia-Gutierrez, R. Cencic, K. Patel, S. Huang, L. E. Brown, A. Emili, J. A. Porco

The paper develops a method to discover RNA-protein-small molecule complexes using proteome-wide stability assays and applies it to identify novel DDX helicase targets of rocaglates.

Journal of Proteome Research · Mar 13, 2025Peer-reviewedBiochemistry

Zhx2 is a candidate gene underlying oxymorphone metabolite brain concentration associated with state-dependent oxycodone reward

J. A. Beierle, E. J. Yao, S. I. Goldstein, W. B. Lynch, J. L. Scotellaro, K. D. Sena, A. L. Wong, C. A. Linnertz, O. Averin, D. E. Moody, C. A. Reilly, G. A. Peltz, A. Emili, M. T. Ferris, C. D. Bryant

This study identifies Zhx2 as a candidate gene influencing oxymorphone brain concentrations and state-dependent oxycodone reward in female mice.

bioRxiv · Mar 18, 2022Pharmacology & Toxicology

Macrophages govern antiviral responses in human lung tissues protected from SARS-CoV-2 infection

D. J. Kenney, A. K. O'Connell, J. Turcinovic, P. Montanaro, R. M. Hekman, T. Tamura, A. R. Berneshawi, T. R. Cafiero, S. Al Abdullatif, B. Blum, S. I. Goldstein, B. Heller, H. P. Gertje, E. Bullitt, A. J. Trachtenberg, , F. Douam

This study shows that macrophages mediate antiviral responses in human lung tissues, protecting against SARS-CoV-2 infection through the USP18-ISG15 axis.

bioRxiv · Jul 17, 2021 · PreprintMicrobiology