Author

M. V. Neguembor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:Hi-C· 1

Frequent Co-Authors

M. P. Cosma· 2 shared A. Bhamra· 1 shared A. Kant· 1 shared D. Pezic· 1 shared E. Pujadas· 1 shared H. Porter· 1 shared L. M. Almassalha· 1 shared L. Martin· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

M. P. Cosma

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Author profile →

2 papers

Recent·Most cited

Active Transcription and Epigenetic Reactions Synergistically RegulateMeso-Scale Genomic Organization

A. Kant, Z. Guo, V. Vinayak, M. V. Neguembor, W. S. Li, V. Agrawal, E. Pujadas, L. M. Almassalha, V. Backman, M. Lakadamyali, M. P. Cosma, V. Shenoy

This study introduces a mesoscale model to show how transcription and epigenetic reactions regulate heterochromatin domain sizes, finding that transcription loss increases domain size and compaction.

bioRxiv · Apr 21, 2023Biophysics

Cohesin-independent STAG proteins interact with RNA and localise to R-loops to promote complex loading.

H. Porter, Y. Li, W. Varsally, M. V. Neguembor, M. Beltran, D. Pezic, L. Martin, M. Tavares Cornejo, A. Bhamra, S. Surinova, R. G. Jenner, M. P. Cosma, S. HADJUR

The paper shows SA proteins interact with RNA and R-loops to promote cohesin loading independently of NIPBL, revealing a new role in chromatin structure and cancer biology.

bioRxiv · Feb 20, 2021Cell Biology