Author

A. L. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. S. Moon· 1 shared B. F. Cravatt· 1 shared B. K. Kennedy· 1 shared E. R. Valentine· 1 shared G. M. Solis· 1 shared J. A. Wohlschlegel· 1 shared J. H. Chern· 1 shared J. R. Williamson· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. S. Moon

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A novel Toxoplasma IMC sutures-associated protein regulates suture protein targeting and colocalizes with membrane trafficking machinery

J. H. Chern, A. S. Moon, A. L. Chen, J. Sha, J. A. Wohlschlegel, P. J. Bradley

This study identifies a novel Toxoplasma gondii protein that localizes to IMC sutures, regulates suture protein targeting, and colocalizes with membrane trafficking machinery.

bioRxiv · Jun 22, 2021Microbiology

Translation Attenuation by Minocycline Increases Lifespan and Improves Proteostasis in Old Post-Stress-Responsive Organisms

G. M. Solis, R. Kardakaris, E. R. Valentine, L. Bar-Peled, A. L. Chen, M. M. Blewett, M. A. McCormick, J. R. Williamson, B. K. Kennedy, B. F. Cravatt, M. Petrascheck

This study shows minocycline extends lifespan and reduces protein aggregation in old C. elegans by inhibiting translation of highly expressed mRNAs, improving proteostasis without activating stress pathways.

bioRxiv · Jul 19, 2018 · PreprintPhysiology