Author

A. L. Dent

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 4 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Liu· 2 shared A. C. Poholek· 1 shared A. Hettinga· 1 shared A. K. Iyer· 1 shared A. Ray· 1 shared A. V. Villarino· 1 shared B. Zhou· 1 shared C. D. Morrow· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

J. Liu

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5 papers

Recent·Most cited

Nuclear proteins acquiring Germinal Center B cells are specifically suppressed by follicular regulatory T cells.

F. Ke, Z. L. Benet, M. P. Maz, J. Liu, A. L. Dent, J. M. Kahlenberg, I. L. Grigorova

The paper shows that follicular regulatory T cells (Tfrs) suppress GC B cells acquiring nuclear proteins, indicating direct Tfr-GC B cell interactions regulate effector B cell responses.

bioRxiv · Oct 25, 2022Immunology

STAT3 expression in dendritic cells protects mice from colitis by a gut microbiome-dependent mechanism

J. Liu, K. Szilagyi, M. Capitano, A. K. Iyer, J. He, M. Olson, J. Du, W. Van Der Pol, C. D. Morrow, B. Zhou, M. Kaplan, A. L. Dent, R. Brutkiewicz

This study shows that STAT3 deficiency in dendritic cells leads to colitis in mice, which is dependent on the gut microbiome.

bioRxiv · Jul 31, 2021 · PreprintImmunology

Broadly reactive influenza antibodies are not limited by germinal center competition with high affinity antibodies

R. Keating, J. L. Johnson, D. C. Brice, J. G. Labombarde, A. L. Dent, M. A. McGargill

This study shows that reducing germinal center competition does not increase broadly reactive influenza antibodies, challenging the hypothesis that competition limits their generation.

bioRxiv · May 11, 2020Immunology

Blimp-1 is essential for Th2 cell development and allergic asthma

K. He, A. Hettinga, S. L. Kale, S. Hu, M. M. Xie, A. L. Dent, A. Ray, A. C. Poholek

This study identifies Blimp-1 as a positive regulator of Th2 cell development and allergic asthma through an IL-10-STAT3-Blimp-1 circuit.

bioRxiv · Jan 2, 2020Immunology

Increased Th1 bias in memory T cells corresponds with protection from reinfection in Plasmodium infection, and is regulated by T cell-intrinsic STAT3

V. H. Carpio, F. Aussenac, K. D. Wilson, A. V. Villarino, A. L. Dent, R. Stephens

The paper shows that STAT3 regulates Th1 bias in memory T cells during Plasmodium infection, enhancing protection from reinfection.

bioRxiv · Aug 5, 2019Immunology