Author

A. Laine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

A. Cvrljevic· 1 shared A. Doshi· 1 shared A. Imbert· 1 shared A. Maddocks· 1 shared A. Munier Godebert· 1 shared A. SAFIEDDINE· 1 shared A. Vinit· 1 shared C. Blugeon· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Cvrljevic

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell cycle-dependent mRNA localization in P-bodies

A. SAFIEDDINE, M.-N. Benassy, T. Bonte, F. Slimani, O. Pourcelot, M. Kress, M. Ernoult-Lange, M. Courel, E. Coleno, A. Imbert, A. Laine, A. Munier Godebert, A. Vinit, C. Blugeon, G. Chevreux, , D. Weil

This study examines how mRNA localization to P-bodies changes during the cell cycle, revealing that mRNA dynamics in P-bodies are not solely linked to translation status but are regulated by RNA features and RBPs.

bioRxiv · Apr 16, 2024Cell Biology

A deep learning pipeline for segmentation of Proteus mirabilis colony patterns

A. Doshi, M. Shaw, R. Tonea, R. Minyety, S. Moon, A. Laine, J. Guo, T. Danino

This paper develops a deep learning pipeline to segment macroscopic colony patterns of Proteus mirabilis, achieving high accuracy in identifying colony boundaries and internal ring structures.

bioRxiv · Jan 17, 2022 · PreprintMicrobiology

ID-Seg: An Accurate and Reliable Infant Deep learning Segmentation Framework for Limbic Structures

Y. Wang, F. S. Haghpanah, X. Zhang, K. Santamaria, G. K. d. C. A. Alves, E. Bruno, N. Aw, A. Maddocks, C. S. Duarte, C. E. Monk, A. Laine, J. Posner

ID-Seg improves segmentation accuracy of limbic structures in infant MRI scans, showing strong brain-behavior associations in a medium-size dataset.

bioRxiv · Mar 29, 2021Bioengineering

CIP2A interacts with TopBP1 and is selectively essential for DNA damage-induced basal-like breast cancer tumorigenesis

A. Laine, S. Nagelli, C. Farrington, U. Butt, A. Cvrljevic, J. Vainonen, T. Gronroos, P. Gautam, S. Khan, H. Sihto, X. Qiao, D. Connolly, P. Kronqvist, J. Maurer, K. Wennerberg, , J. Westermarck

This study identifies CIP2A as a subtype-specific driver of DNA damage-induced basal-like breast cancer, showing its role in checkpoint signaling and therapeutic vulnerability.

bioRxiv · Aug 27, 2020Cancer Biology