Author

A. M. Dudek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:CRISPR screen· 2 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. A. Salahudeen· 1 shared B. J. Lesch· 1 shared C. A. Teran· 1 shared C. J. Kuo· 1 shared C. J. Suarez· 1 shared C. M. Lee· 1 shared D. T. Bravo· 1 shared G. Bao· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

A. A. Salahudeen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Combining Cell-Intrinsic and -Extrinsic Resistance to HIV-1 By Engineering Hematopoietic Stem Cells for CCR5 Knockout and B Cell Secretion of Therapeutic Antibodies

W. N. Feist, S. E. Luna, K. Ben-Efraim, M. V. Filsinger Interrante, N. A. Amorin, N. M. Johnston, T. U. J. Bruun, H. Y. Ghanim, B. J. Lesch, A. M. Dudek, M. H. Porteus

This paper describes engineering hematopoietic stem cells to produce CCR5 knockout cells and secrete HIV-1 inhibiting antibodies, aiming for a one-time cure for HIV-1.

bioRxiv · Mar 8, 2024 · PreprintBioengineering

Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus

S. Vaidyanathan, R. Baik, L. Chen, D. T. Bravo, C. J. Suarez, S. M. Abazari, A. A. Salahudeen, A. M. Dudek, C. A. Teran, T. H. Davis, C. M. Lee, G. Bao, S. H. Randell, S. E. Artandi, J. J. Wine, , M. Porteus

This study corrects multiple CFTR mutations in human airway stem cells using CRISPR/Cas9 and AAV vectors, achieving functional restoration in differentiated epithelial cells.

bioRxiv · Feb 26, 2021Bioengineering