Author

C. J. Suarez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. J. Kuo· 2 shared A. A. Salahudeen· 1 shared A. Khan· 1 shared A. M. Dudek· 1 shared A. Mah· 1 shared A. Sockell· 1 shared B. Lu· 1 shared C. A. Teran· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

C. J. Kuo

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Deterministic evolution and stringent selection during pre-neoplasia

K. Karlsson, M. J. Przybilla, E. Kotler, A. Khan, H. Xu, K. Karagyozova, A. Sockell, W. H. Wong, K. Liu, A. Mah, Y.-H. Lo, B. Lu, K. E. Houlahan, Z. Ma, C. J. Suarez, , C. Curtis

This study models pre-neoplasia in human gastric organoids by inactivating TP53, revealing progression to malignant transcriptional programs and clonal dynamics through experimental evolution.

bioRxiv · Apr 9, 2022 · PreprintCancer Biology

Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus

S. Vaidyanathan, R. Baik, L. Chen, D. T. Bravo, C. J. Suarez, S. M. Abazari, A. A. Salahudeen, A. M. Dudek, C. A. Teran, T. H. Davis, C. M. Lee, G. Bao, S. H. Randell, S. E. Artandi, J. J. Wine, , M. Porteus

This study corrects multiple CFTR mutations in human airway stem cells using CRISPR/Cas9 and AAV vectors, achieving functional restoration in differentiated epithelial cells.

bioRxiv · Feb 26, 2021Bioengineering