Author

A. M. Gronenborn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

A. J. Guseman· 1 shared A. Kleinpeter· 1 shared B. K. Ganser-Pornillos· 1 shared C. M. Quinn· 1 shared C. N. Roy· 1 shared C. Xu· 1 shared D. Martinez· 1 shared D. T. Yang· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. J. Guseman

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Author profile →

2 papers

Recent·Most cited

Structural Basis of HIV-1 Maturation Inhibitor Binding and Activity

S. Sarkar, K. K. Zadrozny, R. Zadorozhnyi, R. W. Russell, C. M. Quinn, A. Kleinpeter, S. Ablan, C. Xu, J. R. Perilla, E. O. Freed, B. K. Ganser-Pornillos, O. Pornillos, A. M. Gronenborn, T. Polenova

This study determines the structural basis of HIV-1 maturation inhibitor binding and resistance using NMR, revealing an allosteric mechanism and conformational changes in SP1 variants.

Nature Communications · Mar 4, 2023Peer-reviewedBiophysics

Targeting Spike Glycans to Inhibit SARS-CoV2 Viral Entry

A. J. Guseman, L. J. Rennick, S. Nambulli, C. N. Roy, D. Martinez, D. T. Yang, F. Bhinderwhala, S. Vergara, R. S. Baric, Z. Ambrose, W. P. Duprex, A. M. Gronenborn

This study shows that BOA, a lectin, binds to SARS-CoV-2 Spike glycans and inhibits viral entry at nanomolar concentrations, effective against variants of concern.

bioRxiv · Dec 22, 2022 · PreprintBiochemistry