Exploiting rodent cell blocks for intrinsic resistance to HIV-1 gene expression in human T cells
R. T. Behrens, J. K. Rajashekar, J. Bruce, E. L. Evans, A. M. Hansen, N. Salazar-Quiroz, L. M. Simons, P. Ahlquist, J. F. Hultquist, P. Kumar, N. M. Sherer
This paper edits human T cells to mimic rodent host factors, creating resistance to HIV-1 and related lentiviruses by disrupting key viral protein interactions.
mBio · Oct 31, 2023Peer-reviewedMicrobiology