Author

J. K. Rajashekar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

P. Kumar· 2 shared A. B. Smith· 1 shared A. Finzi· 1 shared A. M. Hansen· 1 shared B. F. Haynes· 1 shared B. H. Hahn· 1 shared D. R. Burton· 1 shared E. L. Evans· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

P. Kumar

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Exploiting rodent cell blocks for intrinsic resistance to HIV-1 gene expression in human T cells

R. T. Behrens, J. K. Rajashekar, J. Bruce, E. L. Evans, A. M. Hansen, N. Salazar-Quiroz, L. M. Simons, P. Ahlquist, J. F. Hultquist, P. Kumar, N. M. Sherer

This paper edits human T cells to mimic rodent host factors, creating resistance to HIV-1 and related lentiviruses by disrupting key viral protein interactions.

mBio · Oct 31, 2023Peer-reviewedMicrobiology

HIV-1 Vpu restricts Fc-mediated effector functions in vivo

J. Prevost, S. P. Anand, J. K. Rajashekar, J. Richard, G. Goyette, H. Medjahed, G. Gendron-Lepage, H.-C. Chen, Y. Chen, J. A. Horwitz, M. W. Grunst, S. Zolla-Pazner, B. F. Haynes, D. R. Burton, R. A. Flavell, , A. Finzi

This study shows that HIV-1 Vpu reduces nnAb recognition and ADCC resistance, with nnAb Fc-effector functions dependent on Env's open conformation.

bioRxiv · Feb 21, 2022Microbiology