Deterioration of Glutaraldehyde Crosslinked Heterograft Biomaterials due to Advanced Glycation End Product Formation and Serum Albumin Infiltration
C. A. Rock, S. Keeney, A. Zakharchenko, H. Takano, D. A. Spiegel, A. M. Krieger, G. Ferrari, R. J. Levy
This study investigates how AGE formation and serum albumin infiltration degrade glutaraldehyde crosslinked biomaterials, leading to structural and mechanical deterioration in bioprosthetic heart valves.
bioRxiv · May 28, 2020 · PreprintBiophysics