Author

J. B. Grau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

G. Ferrari· 3 shared A. Frasca· 2 shared D. Spiegel· 2 shared E. Castillero· 2 shared J. E. Bavaria· 2 shared R. J. Levy· 2 shared Y. Xue· 2 shared , H. J. Shukla· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersPhysiology

G. Ferrari

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Author profile →

3 papers

Recent·Most cited

RAGE antagonist peptide mitigates AGE-mediated endothelial hyperpermeability and accumulation of glycoxidation products in human ascending aortas and in a murine model of aortic aneurysm

C. Camillo, A. Abramov, P. M. Allen, E. Castillero, E. Roberts, Y. Xue, A. Frasca, V. Moreno, M. Kurade, K. Robinson, D. Spiegel, D. LaPar, J. B. Grau, R. Assoian, J. E. Bavaria, , G. Ferrari

bioRxiv · Oct 22, 2021 · PreprintPhysiology

Inhibition and down regulation of the serotonin transporter contribute to the progression of degenerative mitral regurgitation

R. J. Levy, E. Fitzpatrick, E. Castillero, , H. J. Shukla, , V. V. Inamdar, A. E. Aghali, J. B. Grau, N. Rioux, E. Salvati, S. J. Keeney, I. Nissim, R. C. C. Gorman, L. Rauova, S. J. Stachelek, C. R. Brown, , G. Ferrari

This study investigates how inhibition and downregulation of the serotonin transporter (SLC6A4) contribute to the progression of degenerative mitral regurgitation through enhanced HTR2B signaling.

bioRxiv · Mar 10, 2020 · PreprintPhysiology

Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves

A. Frasca, Y. Xue, A. P. Kossar, S. Keeney, C. Rock, A. Zakharchenko, M. Streeter, R. C. Gorman, J. B. Grau, I. George, J. E. Bavaria, A. Krieger, D. Spiegel, R. J. Levy, G. Ferrari

This study shows glycation and serum albumin infiltration contribute to structural degeneration of bioprosthetic heart valves through mechanisms observed in both clinical samples and in vitro models.

bioRxiv · Feb 14, 2020Bioengineering