Author

A. N. Singh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Bioengineering· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Research Focus:clustering· 1

Frequent Co-Authors

N. J. Wittenberg· 3 shared A. C. Brown· 2 shared B. Vaz· 2 shared I. Torrecilla· 2 shared K. Ramadan· 2 shared M. Popovic· 2 shared A. Bhandawat· 1 shared A. I. McDarby· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersBiophysics

N. J. Wittenberg

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Engineering Planar Gram-Negative Outer Membrane Mimics Using Bacterial Outer Membrane Vesicles

A. N. Singh, M. Wu, T. T. Ye, A. C. Brown, N. J. Wittenberg

This study develops a method to create planar bacterial outer membrane mimics using OMVs, enabling antibiotic development studies by replicating the gram-negative membrane barrier.

bioRxiv · Dec 11, 2023Bioengineering

Identifying size-dependent toxin sorting in bacterial outer membrane vesicles

A. N. Singh, J. B. Nice, A. C. Brown, N. J. Wittenberg

This study uses fluorescence imaging to show that larger OMVs from A. actinomycetemcomitans are more likely to contain leukotoxin, revealing size-dependent toxin sorting.

bioRxiv · May 3, 2023 · PreprintBiophysics

Imaging Giant Vesicle Membrane Domains with a Luminescent Europium Tetracycline Complex

J. L. Cawley, B. A. Berger, A. T. Odudimu, A. N. Singh, D. E. Santa, A. I. McDarby, A. R. Honerkamp-Smith, N. J. Wittenberg

This paper introduces a europium tetracycline complex (EuTc) for imaging membrane microdomains in giant unilamellar vesicles, showing it preferentially labels liquid disordered domains and alters lipid dynamics.

bioRxiv · Jul 1, 2022Biophysics

Population structure and genetic diversity of chickpea germplasms

D. jayaswal, g. Yadav, K. Jayaswall, A. Bhandawat, A. N. Singh, J. Tilgam, A. K. Rai, R. Chaturvedi, A. Kumar, S. Kumar

This study analyzes genetic diversity and population structure of 50 chickpea germplasms using ISSR markers, identifying diverse accessions for breeding and conservation.

bioRxiv · Aug 4, 2021 · PreprintEcology

SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

B. Vaz, A. Ruggiano, M. Popovic, G. Rodriguez-Berriguete, S. Kilgas, A. N. Singh, I. Torrecilla, G. Higgins, A. Kiltie, K. Ramadan

This study identifies SUMO-1 modification of DNA-protein crosslinks (DPCs) as a mechanism that promotes SPRTN proteolysis over homologous recombination, preventing genomic instability.

bioRxiv · Feb 14, 2020 · PreprintCell Biology

SPRTN Protease and Checkpoint Kinase 1 Cross-Activation Loop Safeguards DNA Replication

S. Halder, I. Torrecilla, M. Burkhalter, M. Popovic, J. Fielden, B. Vaz, J. Oehler, D. Pilger, D. Lessel, K. Wiseman, A. N. Singh, I. Vendrell, R. Fischer, M. Philipp, K. Ramadan

This paper shows SPRTN protease and CHK1 form a cross-activation loop to protect DNA replication from stress by regulating CHK1 chromatin eviction and DPC removal.

bioRxiv · Oct 31, 2018Cell Biology