Dicarboxylic acid supplementation protects from acute kidney injury via stimulation of renal peroxisomal activity
A. C. S. Barbosa, K. E. Pfister, T. Chiba, J. Bons, J. Rose, J. B. Burton, C. D. King, A. O'Broin, V. Young, B. Zhang, B. Sivakama, A. V. Schmidt, R. Uhlean, B. Schilling, E. S. Goetzman, S. Sims-Lucas
This study shows that DC8 supplementation reduces AKI markers and promotes peroxisomal FAO over mitochondrial FAO in mice with kidney injury.
bioRxiv · May 31, 2023Pathology