Author

S. Sims-Lucas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

T. Chiba· 2 shared A. C. S. Barbosa· 1 shared A. Hill· 1 shared A. J. Davidson· 1 shared A. O'Broin· 1 shared A. Przepiorski· 1 shared A. Silva-Barbosa· 1 shared A. V. Schmidt· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPathology

T. Chiba

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dicarboxylic acid supplementation protects from acute kidney injury via stimulation of renal peroxisomal activity

A. C. S. Barbosa, K. E. Pfister, T. Chiba, J. Bons, J. Rose, J. B. Burton, C. D. King, A. O'Broin, V. Young, B. Zhang, B. Sivakama, A. V. Schmidt, R. Uhlean, B. Schilling, E. S. Goetzman, S. Sims-Lucas

This study shows that DC8 supplementation reduces AKI markers and promotes peroxisomal FAO over mitochondrial FAO in mice with kidney injury.

bioRxiv · May 31, 2023Pathology

Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization, and de novo cell types

J. C. Maggiore, R. LeGraw, A. Przepiorski, J. Velazquez, C. Chaney, E. Streeter, A. Silva-Barbosa, J. Franks, J. Hislop, A. Hill, H. Wu, K. Pfister, S. E. Howden, S. C. Watkins, M. Little, , N. A. Hukriede

This paper genetically engineers an endothelial niche in human kidney organoids to enhance vascularization, maturation, and the emergence of new cell types.

bioRxiv · May 30, 2023Bioengineering

Metformin preconditioning protects against myocardial stunning and preserves mitochondrial dynamics and protein translation in a mouse model of cardiac arrest

C. Rutledge, C. Lagranha, T. Chiba, K. Redding, D. Stolz, E. Goetzman, S. Sims-Lucas, B. A. Kaufman

This study shows metformin pretreatment protects against cardiac and renal damage after cardiac arrest in mice through AMPK activation, preserving protein translation and mitochondrial function.

bioRxiv · Aug 24, 2021 · PreprintPhysiology