J. P. Rose

Localization and Quantification of Post-Translational Modifications of Proteins Using Electron Activated Dissociation Fragmentation on a Fast-Acquisition Time-of-Flight Mass Spectrometer

This study compares electron activated dissociation (EAD) to collision-induced dissociation (CID) for characterizing and quantifying labile protein post-translational modifications using a fast-acquisition mass spectrometer.

Liver Fibroblast Growth Factor 21 (FGF21) is Required for the Full Anorectic Effect of the Glucagon-Like Peptide-1 Receptor Agonist Liraglutide in Male Mice fed High Carbohydrate Diets

This study shows that FGF21 is necessary for liraglutide's full weight loss effect in male mice on high-carbohydrate diets, mediated through neuronal pathways.

Deep Coverage and Quantification of the Bone Proteome Provides Enhanced Opportunities for New Discoveries in Skeletal Biology and Disease

This paper introduces a novel mass spectrometric workflow for deep bone proteome coverage and quantification, identifying key proteins and post-translational modifications relevant to bone aging and disease.

Ketone body metabolism declines with age in mice in a sex-dependent manner

This study shows that ketone body metabolism declines with age in mice, with sex-dependent differences in metabolic responses to a ketogenic diet.

Accounting for within-species variation in continuous trait evolution on a phylogenetic network

This paper introduces a phylogenetic linear model for network-based comparative methods to account for within-species variation in continuous traits, showing its effectiveness through simulations and application to Polemonium data.