Author

R. Bai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1 Cell Biology· 1 Ecology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:imaging· 2 Assay:CRISPR screen· 1 Assay:cryo-EM· 1 Approach:deep learning· 1

Frequent Co-Authors

A. O'Broin· 1 shared A. Urisman· 1 shared B. Schilling· 1 shared B. Shen· 1 shared C. Chen-Tanyolac· 1 shared C. Ke· 1 shared C. Yan· 1 shared D. Benjamini· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCancer Biology

A. O'Broin

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Optimization of gene knockout approaches and practical solutions to sgRNA selection challenges in hPSCs with inducible Cas9 system

J. Ni, J. Gong, Y. Ran, R. Bai, P. Huang, M. Zhou, Z. Zheng, Y. You, F. Lan, X. Liu

This study optimizes gene knockout in hPSCs using an inducible Cas9 system and identifies effective sgRNAs by comparing experimental results with cleavage efficiency algorithms.

bioRxiv · Jul 9, 2024 · PreprintCell Biology

Human disturbance increases spatiotemporal associations among mountain forest terrestrial mammal species

X. Li, W. V. Bleisch, W. Hu, Q. Li, H. Wang, Z. Chen, R. Bai, X. Jiang

The paper examines how human disturbance affects spatiotemporal associations among mountain forest terrestrial mammals using camera-trap data from the eastern Himalaya.

bioRxiv · Sep 28, 2023Ecology

Data-Independent Acquisition and Quantification of Extracellular Matrix from Human Lung in Chronic Inflammation-Associated Carcinomas

J. Bons, D. Pan, S. Shah, R. Bai, C. Chen-Tanyolac, X. Wang, D. R. Fels Elliott, A. Urisman, A. O'Broin, N. Basisty, J. Rose, V. Sangwan, S. Camilleri-Broet, J. Tankel, P. Gascard, , B. Schilling

The paper develops a proteomic pipeline to analyze ECM remodeling in lung squamous cell carcinoma, identifying 529 differentially expressed proteins and potential biomarkers.

bioRxiv · Aug 5, 2022Cancer Biology

Magnetic Resonance measurements of cellular and sub-cellular membrane structures in live and fixed neural tissue

N. H. Williamson, R. Ravin, D. Benjamini, H. Merkle, M. Falgairolle, M. J. O'Donovan, D. Blivis, D. Ide, T. X. Cai, N. S. Gorash, R. Bai, P. Basser

This study develops MR methods to measure real-time changes in tissue microstructure and membrane permeability in live and fixed neural tissue, revealing water diffusion behavior related to lipid membranes.

bioRxiv · Nov 21, 2019Biophysics

Extensive adaptive immune response of AAVs and Cas proteins in non-human primates

Y. Chen, P. Xiao, R. Bai, T. Zhang, Y. Zhou, Z. Zhou, Y. Zhuo, N. Gong, J. Liu, S. Ren, R. Wu, B. Shen, S. Li, Y. Niu, W. Ji

The paper investigates pre-existing adaptive immune responses to CRISPR Cas proteins and AAVs in non-human primates and finds such immunity is普遍存在 regardless of Cas proteins or AAVs.

bioRxiv · Mar 25, 2019Immunology

Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching

R. Wan, R. Bai, C. Yan, J. Lei, Y. Shi

The paper determines cryo-EM structures of yeast spliceosome B* complexes to elucidate the mechanism of the branching reaction during pre-mRNA splicing.

bioRxiv · Dec 19, 2018Biophysics

Molecular evolution, diversity and adaptation of H7N9 influenza A viruses in China

J. Lu, J. Raghwani, J. Wu, R. Pryce, T. A. Bowden, J. Theze, S. Huang, Y. Song, L. Zou, L. Liang, R. Bai, Y. Jin, P. Zhou, M. Kang, L. Yi, , C. Ke

The paper analyzes the evolution and adaptation of H7N9 influenza viruses in China, identifying lineage-specific mutations and high-pathogenicity strains.

bioRxiv · Jun 25, 2017Evolutionary Biology