Author

T. Chiba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pathology· 2 Physiology· 2 Biochemistry· 1 Cell Biology· 1 Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Organism:mouse· 5 Assay:proteomics· 4 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1

Frequent Co-Authors

B. A. Kaufman· 2 shared K. Redding· 2 shared S. Sims-Lucas· 2 shared A. C. S. Barbosa· 1 shared A. O'Broin· 1 shared A. V. Schmidt· 1 shared Akatsuki KimuraiD· 1 shared B. Schilling· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

B. A. Kaufman

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Anisotropic regulation of lateral surface tension directs invagination in C. elegans gastrulation

T. Katayama, K. Yamamoto, T. Chiba, M. Imai, F. Motegi, Akatsuki Kimura

The paper shows that anisotropic lateral surface tension, mediated by HMR-1/E-cadherin, directs invagination in C. elegans gastrulation, complementing apical constriction.

bioRxiv · Nov 9, 2026 · PreprintDevelopmental Biology

Dicarboxylic acid supplementation protects from acute kidney injury via stimulation of renal peroxisomal activity

A. C. S. Barbosa, K. E. Pfister, T. Chiba, J. Bons, J. Rose, J. B. Burton, C. D. King, A. O'Broin, V. Young, B. Zhang, B. Sivakama, A. V. Schmidt, R. Uhlean, B. Schilling, E. S. Goetzman, S. Sims-Lucas

This study shows that DC8 supplementation reduces AKI markers and promotes peroxisomal FAO over mitochondrial FAO in mice with kidney injury.

bioRxiv · May 31, 2023Pathology

Microbiome ssRNA as an environmental cue to activate TLR13-dependent tissue-protective programs in CD5Lhi hepatic macrophages

R. Sato, K. Liu, T. Shibata, K. Hoshino, K. Yamaguchi, T. Miyazaki, R. Hiranuma, R. Fukui, Y. Motoi, Y. Fukuda-Ohta, Y. Zhang, T. Reuter, Y. Ishida, T. Kondo, T. Chiba, , K. MIYAKE

The paper shows that microbiome ssRNA activates TLR13 in hepatic macrophages to drive tissue-protective responses, leading to resistance against acute liver injury in Rnaset2-/- mice.

bioRxiv · May 11, 2023 · PreprintImmunology

ECPAS/Ecm29-Mediated 26S Proteasome Disassembly Is an Adaptive Response to Glucose Starvation

W. H. Choi, Y. Yun, I. Byun, S. Lee, J. Sim, S. Levi, S. Kim, S. H. Park, J. Jun, K. P. Kim, Y. T. Kwon, D. Han, T. Chiba, C. Seok, M. H. Glickman, M. J. Lee

This study shows that ECPAS-mediated 26S proteasome disassembly into 20S and 19S subcomplexes occurs during glucose starvation, enhancing proteolysis and cell survival.

bioRxiv · Jun 6, 2022Biochemistry

Metformin preconditioning protects against myocardial stunning and preserves mitochondrial dynamics and protein translation in a mouse model of cardiac arrest

C. Rutledge, C. Lagranha, T. Chiba, K. Redding, D. Stolz, E. Goetzman, S. Sims-Lucas, B. A. Kaufman

This study shows metformin pretreatment protects against cardiac and renal damage after cardiac arrest in mice through AMPK activation, preserving protein translation and mitochondrial function.

bioRxiv · Aug 24, 2021 · PreprintPhysiology

A novel ultrasound-guided mouse model of sudden cardiac arrest

C. A. Rutledge, T. Chiba, K. Redding, C. Dezfulian, S. Simms-Lucas, B. A. Kaufman

This paper develops an ultrasound-guided method to induce sudden cardiac arrest in mice, showing rapid asystole and reliable survival rates with secondary organ damage but no neurologic dysfunction.

bioRxiv · Jul 27, 2020Physiology

Proteasome activator PA200 maintains stability of histone marks during transcription and aging

T. Jiang, S. Ma, X. Han, Z. Luo, Q. Zhu, T. Chiba, W. Xie, S. Chen, K. Lin, X. Qiu

This study shows that PA200 maintains histone mark stability during transcription and aging by promoting acetylation-dependent degradation of core histones.

bioRxiv · Apr 28, 2020Cell Biology

Morphogenesis of giant telomeric nuclear bodies in cancer cells with alternative lengthening of telomeres

H. Kamma, Y. arimasu, M. Fujiwara, J. Ishii, T. Chiba, Y. Terado, Y. Shishido-Hara

The paper quantifies giant telomeric nuclear bodies (GT-NBs) in ALT cancer cells and shows they form by aggregating telomeres and associate with PML-NBs.

bioRxiv · Apr 10, 2019 · PreprintPathology