Author

A. P. Gould

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:Drosophila· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. I. MacRae· 2 shared A. Bailey· 1 shared A. Burrell· 1 shared A. Franchet· 1 shared A. Lubojemska· 1 shared A. Martinez-Segura· 1 shared A. Yoshimura· 1 shared B. Stockinger· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCancer Biology

J. I. MacRae

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Author profile →

4 papers

Recent·Most cited

Drosophila AHR limits tumor growth and stem cell proliferation in the intestine

M. Tsai, J. Sun, C. Alexandre, M. Shapiro, A. Franchet, Y. Li, A. P. Gould, J.-P. Vincent, B. Stockinger, N. L. Diny

This study shows that Spineless, the Drosophila AHR homolog, limits tumor growth and stem cell proliferation in the adult intestine by regulating gene expression and metabolism.

bioRxiv · May 17, 2023 · PreprintCancer Biology

Diet suppresses tumour initiation by maintaining quiescence of mutation-bearing neural stem cells

V. Amodeo, T. Davies, A. Martinez-Segura, M. Clements, H. Simpson Ragdale, A. Bailey, M. Silva dos Santos, J. I. MacRae, J. Mokochinski, H. Kramer, C. Garcia-Diaz, A. P. Gould, S. Marguerat, S. Parrinello

This study shows that diet can suppress glioblastoma by restoring quiescence in p53-deficient neural stem cells through omega-3 fatty acids.

bioRxiv · Mar 9, 2022 · PreprintCancer Biology

Adipose Triglyceride Lipase protects the endocytosis of renal cells on a high fat diet in Drosophila

A. Lubojemska, M. I. Stefana, L. Lampe, A. Yoshimura, A. Burrell, L. Collinson, A. P. Gould

This study shows that adipose triglyceride lipase (ATGL) in Drosophila nephrocytes protects against high-fat diet-induced renal endocytosis defects by lipid droplet lipolysis and mitochondrial pathways.

bioRxiv · Nov 19, 2020 · PreprintCell Biology

Cryogenic OrbiSIMS Localizes Semi-Volatile Molecules in Biological Tissues

C. L. Newell, J.-L. Vorng, J. I. MacRae, I. Gilmore, A. P. Gould

This paper introduces Cryo-OrbiSIMS, a cryogenic workflow that improves detection of semi-volatile molecules in tissues, revealing new localization patterns and enabling integration with genetic analysis.

bioRxiv · Dec 2, 2019Biochemistry