Author

S. Marguerat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. Keifenheim· 2 shared N. Rhind· 2 shared S. Parrinello· 2 shared X.-M. Sun· 2 shared A. Bailey· 1 shared A. Martinez-Segura· 1 shared A. P. Gould· 1 shared C. Garcia-Diaz· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

D. Keifenheim

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Post-Transcriptional Size-Dependent Expression of the Fission Yeast Cdc13 Cyclin

S. Bashir, X.-M. Sun, Y. Zhao, N. G. Martinez-Illescas, I. Gallego-Lopez, L. Guerrero Negron, D. Keifenheim, T. Karadimitriou, M. Pickering, S. Marguerat, N. Rhind

This study shows that Cdc13 in fission yeast is size-dependent at the protein level but not at the mRNA level, and identifies a motif responsible for this regulation, demonstrating it is not essential for size control.

bioRxiv · Jan 16, 2023 · PreprintCell Biology

Diet suppresses tumour initiation by maintaining quiescence of mutation-bearing neural stem cells

V. Amodeo, T. Davies, A. Martinez-Segura, M. Clements, H. Simpson Ragdale, A. Bailey, M. Silva dos Santos, J. I. MacRae, J. Mokochinski, H. Kramer, C. Garcia-Diaz, A. P. Gould, S. Marguerat, S. Parrinello

This study shows that diet can suppress glioblastoma by restoring quiescence in p53-deficient neural stem cells through omega-3 fatty acids.

bioRxiv · Mar 9, 2022 · PreprintCancer Biology

The white matter is a pro-differentiative microenvironment for glioblastoma

L. J. Brooks, M. P. Clements, J. J. Burden, D. Kocher, L. Richards, S. Castro Devesa, M. Woodberry, M. Ellis, L. Zakka, Z. Jaunmuktane, S. Brandner, G. Morrison, S. M. Pollard, P. B. Dirks, S. Marguerat, S. Parrinello

This study identifies the white matter as a differentiative niche for glioblastomas, showing that tumour cells in contact with it acquire pre-oligodendrocyte-like fate, leading to reduced proliferation and invasion.

bioRxiv · Nov 14, 2020 · PreprintCancer Biology

A bacterial size law revealed by a coarse-grained model of cell physiology

F. Bertaux, J. Von Kügelgen, S. Marguerat, V. Shahrezaei

The paper introduces a novel size law linking cell size to metabolic proteome mass fraction and ribosome activity, validated through a coarse-grained physiological model.

bioRxiv · Feb 7, 2020Biophysics

Size-Dependent Accumulation of the Mitotic Activator Cdc25 as a Mechanism of Size Control in Fission Yeast

D. Keifenheim, X.-M. Sun, E. D'Souza, M. J. Ohira, M. Magner, M. B. Mayhew, S. Marguerat, N. Rhind

This study identifies a size-dependent Cdc25 expression mechanism in fission yeast that regulates cell size by controlling mitotic entry.

bioRxiv · Feb 28, 2017Cell Biology