Author

A. P. Khandhar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 4 Research Focus:drug response / drug discovery· 3 Organism:rat· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:non-human primate· 1

Frequent Co-Authors

J. Archer· 4 shared D. H. Fuller· 3 shared D. W. Hawman· 3 shared H. Feldmann· 3 shared J. Erasmus· 3 shared M. Gale· 3 shared P. Berglund· 3 shared S. G. Reed· 3 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

J. Archer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine

Z. MacMillen, K. Hatzakis, A. Simpson, M. J. Shears, F. Watson, J. Erasmus, A. P. Khandhar, B. K. Wilder, S. C. Murphy, S. G. Reed, J. W. Davie, M. Avril

This paper develops an accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine that provides sterile protection with a single day regimen.

bioRxiv · May 23, 2023Immunology

RNA-based vaccine demonstrates prophylactic efficacy against Mycobacterium tuberculosis challenge in a mouse model

S. E. Larsen, J. H. Erasmus, V. A. Reese, T. Pecor, J. Archer, A. P. Khandhar, F.-C. Hsu, S. G. Reed, S. L. Baldwin, R. N. Coler

This study evaluates two TB vaccine platforms in mice, showing both reduce bacterial burden, with RNA-based vaccines showing greater efficacy in combination immunization strategies.

bioRxiv · Feb 23, 2022 · PreprintImmunology

Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine

D. W. Hawman, K. Meade-White, C. Clancy, J. Archer, T. Hinkley, S. Leventhal, D. Rao, A. Stamper, M. Lewis, R. Rosenke, K. Krieger, S. Randall, A. P. Khandhar, L. Hao, T.-Y. Hsiang, , J. Erasmus

bioRxiv · Jan 31, 2022Microbiology

SARS-CoV2 variant-specific replicating RNA vaccines protect from disease and pathology and reduce viral shedding following challenge with heterologous SARS-CoV2 variants of concern

D. W. Hawman, K. Meade-White, J. Archer, S. Leventhal, D. Wilson, C. Shaia, S. Randall, A. P. Khandhar, T.-Y. Hsiang, M. Gale, P. Berglund, D. H. Fuller, H. Feldmann, J. Erasmus

This study evaluates a replicating RNA vaccine against SARS-CoV-2 variants, showing protection from disease and reduced viral shedding after heterologous challenge.

bioRxiv · Dec 10, 2021Microbiology

Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates

J. H. Erasmus, A. P. Khandhar, A. C. Walls, E. A. Hemann, M. A. O'Connor, P. Murapa, J. Archer, S. Leventhal, J. Fuller, T. Lewis, K. E. Draves, S. Randall, K. A. Guerriero, M. S. Duthie, D. Carter, , D. H. Fuller

bioRxiv · May 28, 2020 · PreprintImmunology