Author

J. H. Erasmus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:non-human primate· 4 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

D. H. Fuller· 4 shared J. Archer· 4 shared D. W. Hawman· 3 shared S. G. Reed· 3 shared A. Khandhar· 2 shared A. P. Khandhar· 2 shared H. Feldmann· 2 shared K. A. Guerriero· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersImmunology

D. H. Fuller

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Author profile →

6 papers

Recent·Most cited

Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals

A. A. Cohen, J. R. Keeffe, A. Schiepers, S. E. Dross, A. J. Greaney, A. V. Rorick, H. Gao, P. N. P. Gnanapragasam, C. Fan, A. P. West, A. I. Ramsingh, J. H. Erasmus, J. D. Pata, H. Muramatsu, N. Pardi, , P. J. Bjorkman

The paper shows mosaic-8b nanoparticles induce broader cross-reactive antibodies than homotypic ones, even in pre-vaccinated animals, suggesting potential for improved vaccine design against emerging sarbecoviruses.

bioRxiv · Feb 8, 2024Immunology

A replicon RNA vaccine induces durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

M. A. O'Connor, D. W. Hawman, K. Meade-White, S. Leventhal, W. Song, S. Randall, J. Archer, T. B. Lewis, B. Brown, N. Iwayama, C. Ahrens, W. Garrison, S. Wangari, K. A. Guerriero, P. Hanley, , J. H. Erasmus

This study shows a replicon RNA vaccine provides durable protection against SARS-CoV-2 in nonhuman primates even after neutralizing antibodies decline.

bioRxiv · Aug 8, 2022 · PreprintImmunology

RNA-based vaccine demonstrates prophylactic efficacy against Mycobacterium tuberculosis challenge in a mouse model

S. E. Larsen, J. H. Erasmus, V. A. Reese, T. Pecor, J. Archer, A. P. Khandhar, F.-C. Hsu, S. G. Reed, S. L. Baldwin, R. N. Coler

This study evaluates two TB vaccine platforms in mice, showing both reduce bacterial burden, with RNA-based vaccines showing greater efficacy in combination immunization strategies.

bioRxiv · Feb 23, 2022 · PreprintImmunology

Macaque-human differences in SARS-CoV-2 Spike antibody response elicited by vaccination or infection

A. Willcox, K. Sung, M. E. Garrett, J. G. Galloway, M. A. OConnor, J. H. Erasmus, J. K. Logue, D. W. Hawman, H. Y. Chu, K. J. Hasenkrug, D. H. Fuller, F. A. Matsen, J. Overbaugh

This study compares SARS-CoV-2 Spike antibody responses between macaques and humans after vaccination or infection, identifying shared and distinct epitope recognition patterns and escape pathways.

bioRxiv · Dec 1, 2021 · PreprintImmunology

Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates

J. H. Erasmus, A. P. Khandhar, A. C. Walls, E. A. Hemann, M. A. O'Connor, P. Murapa, J. Archer, S. Leventhal, J. Fuller, T. Lewis, K. E. Draves, S. Randall, K. A. Guerriero, M. S. Duthie, D. Carter, , D. H. Fuller

bioRxiv · May 28, 2020 · PreprintImmunology

Integrated technology platform for accelerated discovery of antiviral antibody therapeutics

P. Gilchuk, R. G. Bombardi, J. H. Erasmus, Q. Tan, R. S. Nargi, C. Soto, P. Abbink, T. J. Suscovich, L. A. Dunellin, A. Khandhar, J. Archer, J. Liang, M. E. Fouch, E. Davidson, B. Doranz, , R. H. Carnahan

This study develops an integrated platform to rapidly discover and validate potent antiviral human monoclonal antibodies against Zika virus.

bioRxiv · May 12, 2020Immunology