Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms
S. R. Hall, S. A. Rasmussen, E. Crittenden, C. A. Dawson, K. E. Bartlett, A. P. Westhorpe, L.-O. Albulescu, J. Kool, J. M. Gutierrez, N. R. Casewell
The paper shows repurposed drugs and their combinations reduce cytotoxicity of snake venoms in cell and mouse models, offering potential new treatments for snakebite envenoming.
bioRxiv · May 20, 2022Pharmacology & Toxicology