Author

A. Pedoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:zebrafish· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Martinez-Lopez· 2 shared S. Candel· 2 shared S. D. Tyrkalska· 2 shared V. Mulero· 2 shared J. A. Ros-Lucas· 1 shared M. L. Cayuela· 1 shared P. Mesa-del-Castillo· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

A. Martinez-Lopez

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A zebrafish model of COVID-19-associated cytokine storm syndrome reveals that the Spike protein signals via TLR2

S. D. Tyrkalska, A. Martinez-Lopez, A. Pedoto, S. Candel, M. L. Cayuela, V. Mulero

This study shows that the S1 domain of SARS-CoV-2 Spike protein induces hyperinflammation in zebrafish larvae via Tlr2/Myd88 signaling, independent of IL-1β, and also triggers emergency myelopoiesis through a Tlr2/Myd88-independent pathway.

bioRxiv · Jul 14, 2022 · PreprintImmunology

Combination therapy targeting inflammasome and fibrogenesis alleviates inflammation and fibrosis in a zebrafish model of silicosis

S. D. Tyrkalska, A. Pedoto, A. Martinez-Lopez, S. Candel, J. A. Ros-Lucas, P. Mesa-del-Castillo, V. Mulero

This study uses a zebrafish model of silicosis to show that combining an inflammasome inhibitor and antifibrotic agent reduces inflammation and fibrosis.

bioRxiv · May 4, 2022 · PreprintImmunology