Author

M. L. Cayuela

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:zebrafish· 5 Research Focus:host-pathogen & immune response· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

V. Mulero· 5 shared D. Garcia-Moreno· 4 shared A. Martinez-Lopez· 2 shared F. J. Martinez-Morcillo· 2 shared M. C. Mione· 2 shared S. Candel· 2 shared S. D. Tyrkalska· 2 shared A. B. Arroyo· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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5 shared papersImmunology

V. Mulero

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A zebrafish model of COVID-19-associated cytokine storm syndrome reveals that the Spike protein signals via TLR2

S. D. Tyrkalska, A. Martinez-Lopez, A. Pedoto, S. Candel, M. L. Cayuela, V. Mulero

This study shows that the S1 domain of SARS-CoV-2 Spike protein induces hyperinflammation in zebrafish larvae via Tlr2/Myd88 signaling, independent of IL-1β, and also triggers emergency myelopoiesis through a Tlr2/Myd88-independent pathway.

bioRxiv · Jul 14, 2022 · PreprintImmunology

A zebrafish model of COVID-19-associated cytokine storm syndrome reveals differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern.

S. D. Tyrkalska, A. Martinez-Lopez, A. B. Arroyo, F. J. Martinez-Morcillo, S. Candel, P. Mesa-del-Castillo, D. Garcia-Moreno, M. L. Cayuela, V. Mulero

This paper uses a zebrafish model to study the proinflammatory effects of SARS-CoV-2 Spike proteins from different variants, finding differential inflammatory responses and potential therapeutic targets.

bioRxiv · Dec 5, 2021 · PreprintImmunology

NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos

F. J. Martinez-Morcillo, J. Canton-Sandoval, F. J. Martinez-Navarro, I. cabas, I. Martinez-Vicente, J. Armistead, J. Hatzold, A. Lopez-Munoz, T. Martinez-Menchon, R. Corbalan-Velez, J. Lacal, M. Hammerschmidt, J. C. Garcia-Borron, A. Garcia-Ayala, M. L. Cayuela, , V. Mulero

This study shows that NAMPT-derived NAD+ fuels PARP1 to drive skin inflammation via parthanatos in psoriasis models.

bioRxiv · Feb 19, 2021Immunology

TERT-mediated induction of MIR500A contributes to tumor invasiveness by targeting Hedgehog pathway

M. Bernabe-Garcia, E. Martinez-Balsalobre, D. Garcia-Moreno, J. Garcia-Castillo, B. Revilla-Nuin, E. Blanco-Alcaina, V. Mulero, F. Alcaraz-Perez, M. L. Cayuela

The paper shows TERT promotes cancer invasiveness by inducing MIR500A, which suppresses Hedgehog pathway genes.

bioRxiv · Feb 18, 2020 · PreprintCancer Biology

Expression of telomerase prevents ALT and maintains telomeric heterochromatin in juvenile brain tumors.

A. I. Idilli, E. Cusanelli, F. Pagani, E. Kerschbamer, F. Berardinelli, M. Bernabe, M. L. Cayuela, S. Piazza, P. L. Poliani, M. C. Mione

bioRxiv · Jul 30, 2019 · PreprintCancer Biology

SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment

E. Gomez-Abenza, S. Ibanez-Molero, D. Garcia-Moreno, I. Fuentes-Martinez, L. Zon, M. C. Mione, M. L. Cayuela, C. Gabellini, V. Mulero

The paper shows Spint1a deficiency in zebrafish promotes SKCM aggressiveness by enhancing oncogenic transformation, regulating tumor-immune crosstalk, and accelerating metastasis.

bioRxiv · Apr 16, 2019Cancer Biology