Combination therapy targeting inflammasome and fibrogenesis alleviates inflammation and fibrosis in a zebrafish model of silicosis
S. D. Tyrkalska, A. Pedoto, A. Martinez-Lopez, S. Candel, J. A. Ros-Lucas, P. Mesa-del-Castillo, V. Mulero
This study uses a zebrafish model of silicosis to show that combining an inflammasome inhibitor and antifibrotic agent reduces inflammation and fibrosis.
bioRxiv · May 4, 2022 · PreprintImmunology