Author

A. R. Floto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Organism:zebrafish· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Bernut· 2 shared C. Langevin· 2 shared J.-L. Herrmann· 2 shared A. Ait Ali Said· 1 shared A. Weimann· 1 shared B. Bannerman· 1 shared C. Bureau· 1 shared C. Cougoule· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

A. Bernut

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Curcumin-mediated NRF2 induction limits inflammatory damage in preclinical models of cystic fibrosis

S. A. Leon-Icaza, M. Fretaud, S. Cornelie, C. Bureau, L. Yatime, A. R. Floto, S. Renshaw, J.-L. Herrmann, C. Langevin, C. Cougoule, A. Bernut

This study shows curcumin improves inflammation and tissue damage in cystic fibrosis by restoring NRF2 activity in zebrafish and patient-derived airway organoids.

bioRxiv · Mar 17, 2024Immunology

The pathobiology of Mycobacterium abscessus revealed through phenogenomic analysis

L. Boeck, S. Burbaud, M. J. Skwark, W. H. Pearson, J. Sangen, A. Weimann, I. Everall, J. M. Bryant, S. Malhotra, B. Bannerman, K. Kierdorf, T. Blundell, M. S. Dionne, J. Parkhill, A. R. Floto

This study uses phenogenomic analysis to uncover virulence mechanisms and drug resistance in Mycobacterium abscessus by integrating phenotyping, genomics, and computational modeling.

bioRxiv · Oct 18, 2021 · PreprintMicrobiology

Roscovitine exacerbates Mycobacterium abscessus infection by reducing NADPH oxidase-dependent neutrophil trafficking

V. Le Moigne, D. Rodriguez Rincon, S. Glatigny, C. Dupont, C. Langevin, A. Ait Ali Said, S. A. Renshaw, A. R. Floto, J.-L. Herrmann, A. Bernut

This study shows Roscovitine reduces neutrophil trafficking by inhibiting NADPH oxidase, worsening Mycobacterium abscessus infection in CF models.

bioRxiv · Jul 30, 2021 · PreprintMicrobiology