Author

K. Kierdorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Organism:Drosophila· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Organism:mouse· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

M. Prinz· 3 shared M. S. Dionne· 3 shared G. Monaco· 2 shared W. H. Pearson· 2 shared A. K. Lösslein· 1 shared A. R. Floto· 1 shared A. Sifrim· 1 shared A. Weimann· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersImmunology

M. Prinz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Streptococcal meningoencephalitis dynamically shapes developmental monocyte and macrophage trajectories in the CNS

V. Gres, F. Lohrmann, V. Fuchs, J. Neuber, Z. Mansoori Moghadam, A. K. Lösslein, L. F. Pahutan Bosch, T. Figueiral-Martins, S. Baasch, D. Obwegs, G. Monaco, J. Henschel, K. P. Knobeloch, M. Prinz, S. Jung, , P. Henneke

This study shows that streptococcal meningoencephalitis alters monocyte and macrophage dynamics in the dura by shifting their origin from skull bone marrow to peripheral sources and increasing MDP-Mo-derived cells.

bioRxiv · Feb 27, 2024 · PreprintImmunology

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response 1 to oxidative stress

F. Hersperger, T. Meyring, P. Weber, C. Chhatbar, G. Monaco, M. S. Dionne, K. Paeschke, M. Prinz, O. Gross, A.-K. Classen, K. Kierdorf

This study identifies DNA damage signaling in Drosophila macrophages as a key regulator of cytokine release and oxidative stress response through JNK and unpaired-3.

bioRxiv · Feb 22, 2023 · PreprintImmunology

Neuro-immune Crosstalk in the Enteric Nervous System from Early Postnatal Development to Adulthood

M. F. Viola, M. Chavero Pieres, E. Modave, N. Stakenborg, M. Delfini, N. Fabre, I. Appeltans, T. Martens, K. Vandereyken, J. Van Herck, P. Petry, S. Verheijden, S. De Schepper, A. Sifrim, K. KIERDORF, , G. Boeckxstaens

This study shows that intestinal macrophages refine the enteric nervous system early in life by pruning synapses and phagocytosing neurons, and maintain neuron survival post-weaning through a TGFβ-driven microglia-like phenotype.

bioRxiv · May 12, 2022Immunology

The pathobiology of Mycobacterium abscessus revealed through phenogenomic analysis

L. Boeck, S. Burbaud, M. J. Skwark, W. H. Pearson, J. Sangen, A. Weimann, I. Everall, J. M. Bryant, S. Malhotra, B. Bannerman, K. Kierdorf, T. Blundell, M. S. Dionne, J. Parkhill, A. R. Floto

This study uses phenogenomic analysis to uncover virulence mechanisms and drug resistance in Mycobacterium abscessus by integrating phenotyping, genomics, and computational modeling.

bioRxiv · Oct 18, 2021 · PreprintMicrobiology

Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster

C. M. Vincent, E. J. Beckwith, W. H. Pearson, K. Kierdorf, G. Gilestro, M. S. Dionne

This study shows that bacterial infections in Drosophila increase physical activity through Toll-dependent and Toll-independent mechanisms, with activity levels predicting survival.

bioRxiv · Aug 24, 2021Immunology