Author

W. H. Pearson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 1 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. S. Dionne· 4 shared E. J. Beckwith· 2 shared K. Kierdorf· 2 shared A. M. Darby· 1 shared A. M. Frank· 1 shared A. R. Floto· 1 shared A. Weimann· 1 shared B. Bannerman· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersImmunology

M. S. Dionne

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

High sugar diets can increase susceptibility to bacterial infection in Drosophila melanogaster

A. M. Darby, D. O. Okoro, S. N. Aredas, A. M. Frank, W. H. Pearson, M. S. Dionne, B. P. Lazzaro

This study shows high-sugar diets increase susceptibility to certain bacterial infections in Drosophila by impairing antimicrobial peptide production and promoting pathogen growth.

bioRxiv · Dec 7, 2023 · PreprintImmunology

A serine-folate metabolic unit controls resistance and tolerance of infection

K. Grimes, E. J. Beckwith, W. H. Pearson, J. Jacobson, S. Chaudhari, G. N. Aughey, G. Larrouy-Maumus, T. D. Southall, M. S. Dionne

This study identifies a serine-folate metabolic pathway regulated by immune signals in Drosophila that affects infection resistance and tolerance.

bioRxiv · Nov 25, 2022 · PreprintImmunology

The pathobiology of Mycobacterium abscessus revealed through phenogenomic analysis

L. Boeck, S. Burbaud, M. J. Skwark, W. H. Pearson, J. Sangen, A. Weimann, I. Everall, J. M. Bryant, S. Malhotra, B. Bannerman, K. Kierdorf, T. Blundell, M. S. Dionne, J. Parkhill, A. R. Floto

This study uses phenogenomic analysis to uncover virulence mechanisms and drug resistance in Mycobacterium abscessus by integrating phenotyping, genomics, and computational modeling.

bioRxiv · Oct 18, 2021 · PreprintMicrobiology

Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster

C. M. Vincent, E. J. Beckwith, W. H. Pearson, K. Kierdorf, G. Gilestro, M. S. Dionne

This study shows that bacterial infections in Drosophila increase physical activity through Toll-dependent and Toll-independent mechanisms, with activity levels predicting survival.

bioRxiv · Aug 24, 2021Immunology