M. S. Dionne

High sugar diets can increase susceptibility to bacterial infection in Drosophila melanogaster

This study shows high-sugar diets increase susceptibility to certain bacterial infections in Drosophila by impairing antimicrobial peptide production and promoting pathogen growth.

A humoral stress response protects Drosophila tissues from antimicrobial peptides

This study identifies Turandot stress proteins that protect Drosophila tissues from antimicrobial peptide-induced damage by binding phosphatidylserine and inhibiting AMP pore formation.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response 1 to oxidative stress

This study identifies DNA damage signaling in Drosophila macrophages as a key regulator of cytokine release and oxidative stress response through JNK and unpaired-3.

A serine-folate metabolic unit controls resistance and tolerance of infection

This study identifies a serine-folate metabolic pathway regulated by immune signals in Drosophila that affects infection resistance and tolerance.

E. faecalis acquires resistance to antimicrobials and insect immunity via common mechanisms

The paper shows that E. faecalis develops resistance to both antimicrobials and host immunity through shared mechanisms, without requiring antibiotic exposure.

The pathobiology of Mycobacterium abscessus revealed through phenogenomic analysis

This study uses phenogenomic analysis to uncover virulence mechanisms and drug resistance in Mycobacterium abscessus by integrating phenotyping, genomics, and computational modeling.

Pre-copulatory reproductive behaviours are preserved in Drosophila melanogaster infected with bacteria.

This study finds that bacterial infection in Drosophila melanogaster does not significantly affect pre-copulatory reproductive behaviors in males or female sexual receptivity.

Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster

This study shows that bacterial infections in Drosophila increase physical activity through Toll-dependent and Toll-independent mechanisms, with activity levels predicting survival.

Disparate regulation of imd drives sex differences in infection tolerance in Drosophila melanogaster

This study identifies sex-specific immune regulation in Drosophila melanogaster, showing that female-specific PGRP-LB expression reduces immune activity and affects infection tolerance.

EslB is required for cell wall biosynthesis and modification in Listeria monocytogenes

This study shows that EslB, a component of the ABC transporter EslABC, is essential for cell wall biosynthesis and modification in L. monocytogenes, affecting lysozyme resistance, cell division, and growth in high-sugar media.