Author

A. R. Godwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

C. Baldock· 2 shared G. Sengle· 2 shared A. Gerken· 1 shared A. M. Roseman· 1 shared A. Niehoff· 1 shared B. Callewaert· 1 shared C. S. Adamo· 1 shared D. F. Holmes· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

C. Baldock

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Author profile →

2 papers

Recent·Most cited

Fibrillin microfibril structure identifies long-range effects of inherited pathogenic mutations affecting a key regulatory TGFβ-binding site

A. R. Godwin, J. Thomson, D. F. Holmes, C. S. Adamo, G. Sengle, M. J. Sherratt, A. M. Roseman, C. Baldock

The paper reveals the cryo-EM structure of fibrillin microfibrils and shows how mutations disrupt TGFβ signaling by blocking LTBP-1 interaction through long-range structural effects.

bioRxiv · Aug 26, 2022 · PreprintBiochemistry

Transglutaminase mediated asprosin oligomerization allows its tissue storage as fibers

Y. A. Morcos, G. Pryymachuk, S. Luetke, A. Gerken, A. R. Godwin, T. A. Jowitt, N. Piekarek, T. Hoffmann, A. Niehoff, M. Odenthal, U. Drebber, O. Grisk, Y. Ladilov, W. Bloch, B. Callewaert, , G. Sengle

The paper identifies transglutaminase-mediated asprosin oligomerization and extracellular fiber formation in connective tissues, suggesting a new mechanism for tissue storage and regulation of asprosin bioavailability.

bioRxiv · Jan 4, 2022 · PreprintBiochemistry