A. R. Harris

Platinum chemotherapy induces lymphangiogenesis in cancerous and healthy tissues that can be prevented with adjuvant anti-VEGFR3 therapy

Biased localization of actin binding proteins by actin filament conformation

The paper shows that actin-binding proteins preferentially localize to different actin structures based on filament conformation, using live cell imaging and in vitro binding measurements.

Paternal age in rhesus macaques is positively associated with germline mutation accumulation but not with measures of offspring sociability

This study estimates the de novo mutation rate in rhesus macaques and finds it is lower than in humans, but paternal age still correlates with increased mutations. No association is found between paternal age and offspring sociability.

A weak link with actin organizes tight junctions to control epithelial permeability

This study identifies a weak ZO-1-actin interaction that controls epithelial permeability through kinetic trapping, enabling tunable permeability in engineered monolayers.

Steric Regulation of Tandem Calponin Homology Domain Actin-Binding Affinity

The paper investigates how structural modifications affect the actin-binding affinity of tandem CH1-CH2 domains, finding that steric changes and interface mutations influence binding properties and sub-cellular localization.