Author

A. R. Nager

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

M. V. Nachury· 2 shared A. E. Stewart· 1 shared A. M. Gilbert· 1 shared A. Nagata· 1 shared B. F. Cravatt· 1 shared B. Melillo· 1 shared E. Johnson· 1 shared F. Ye· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

M. V. Nachury

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Author profile →

3 papers

Recent·Most cited

Expanding the ligandable proteome by paralog hopping with covalent probes

Y. Zhang, Z. Liu, M. Hirschi, O. Brodsky, E. Johnson, S. J. Won, A. Nagata, M. D. Petroski, J. D. Majmudar, S. Niessen, T. VanArsdale, A. M. Gilbert, M. M. Hayward, A. E. Stewart, A. R. Nager, , B. F. Cravatt

The paper uses covalent probes and paralog hopping to identify ligandable pockets in proteins lacking cysteines, demonstrating a method to expand the ligandable proteome.

bioRxiv · Jan 18, 2024 · PreprintBiochemistry

Lysine63-linked ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia

S. R. Shinde, A. R. Nager, M. V. Nachury

This study shows that K63-linked ubiquitin chains tag GPCRs for BBSome-mediated removal from cilia, requiring β-arrestin and deubiquitinase targeting.

bioRxiv · Mar 4, 2020Cell Biology

BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone

F. Ye, A. R. Nager, M. V. Nachury

The paper shows that BBSome trains transport activated GPCRs across the transition zone, but exit from cilia is hindered by a second diffusion barrier.

bioRxiv · Dec 27, 2017Cell Biology