Author

A. R. Perestrelo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

F. Cavalieri· 2 shared G. Forte· 2 shared S. Pagliari· 2 shared A. P. Gerber· 1 shared D. Debellis· 1 shared D. Sousa· 1 shared E. Ergir· 1 shared F. Caruso· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

F. Cavalieri

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Generation and Maturation of Human iPSC-derived Cardiac Organoids in Long Term Culture

E. Ergir, J. Oliver-de la Cruz, S. Fernandes, M. Cassani, F. Niro, D. Sousa, J. Vrbsky, V. Vinarsky, A. R. Perestrelo, D. Debellis, F. Cavalieri, S. Pagliari, H. Redl, P. Ertl, G. Forte

This study develops a scaffold-free protocol to generate long-term beating human cardiac organoids from hiPSCs, showing improved maturation and functionality for drug testing and cardiotoxicity studies.

bioRxiv · Mar 7, 2022 · PreprintCell Biology

The mechanical regulation of RNA binding protein hnRNPC in the failing heart

F. Martino, N. M. Varadarajan, A. R. Perestrelo, V. Hejret, H. Durikova, V. Horvath, F. Cavalieri, F. Caruso, W. S. Albihlal, A. P. Gerber, M. A. O'Connell, S. Vanacova, S. Pagliari, G. Forte

The paper shows that hnRNPC upregulation and relocation to the Z-disk in failing hearts affects mRNA alternative splicing and mechanotransduction.

bioRxiv · Aug 27, 2021Pathology