Author

F. Caruso

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

F. Cavalieri· 2 shared G. Forte· 2 shared H. Durikova· 2 shared A. Anichini· 1 shared A. Covre· 1 shared A. I. Bush· 1 shared A. M. Di Giacomo· 1 shared A. Manca· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

F. Cavalieri

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

YAP signaling regulates the cellular uptake and therapeutic effect of nanoparticles

M. Cassani, S. Fernandes, J. Oliver-De La Cruz, H. Durikova, J. Vrbsky, M. Patocka, V. Hegrova, S. Klimovic, J. Pribyl, D. Debellis, P. Skladal, F. Cavalieri, F. Caruso, G. Forte

This study shows that inhibiting YAP enhances nanoparticle uptake in triple-negative breast cancer cells, suggesting YAP targeting could improve nanotherapy effectiveness.

bioRxiv · Mar 10, 2023Bioengineering

Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy

A. Anichini, A. Molla, G. Nicolini, V. E. Perotti, F. Sgambelluri, A. Covre, C. Fazio, M. F. Lofiego, A. M. Di Giacomo, S. Coral, A. Manca, M. C. Sini, M. Pisano, T. Noviello, F. Caruso, , R. Mortarini

This paper identifies immune-related gene signatures induced by four epigenetic inhibitors in melanoma cells, finding that guadecitabine most strongly upregulates immune-related genes and activates innate immunity pathways.

bioRxiv · Apr 13, 2022Immunology

mRNA Treatment Rescues Niemann-Pick Disease Type C1 in Patient Fibroblasts

D. Furtado, C. Cortez-Jugo, Y. H. Hung, A. I. Bush, F. Caruso

This paper demonstrates that engineered mRNA can restore NPC1 protein function and correct the pathogenic phenotype in NP-C1 patient fibroblasts.

bioRxiv · Feb 21, 2022Bioengineering

The mechanical regulation of RNA binding protein hnRNPC in the failing heart

F. Martino, N. M. Varadarajan, A. R. Perestrelo, V. Hejret, H. Durikova, V. Horvath, F. Cavalieri, F. Caruso, W. S. Albihlal, A. P. Gerber, M. A. O'Connell, S. Vanacova, S. Pagliari, G. Forte

The paper shows that hnRNPC upregulation and relocation to the Z-disk in failing hearts affects mRNA alternative splicing and mechanotransduction.

bioRxiv · Aug 27, 2021Pathology