Author

A. Reuben

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. C. Chacon· 1 shared A. Williams· 1 shared B. J. Han· 1 shared C. Cheng· 1 shared C. Liang· 1 shared C. Yee· 1 shared C. Zhu· 1 shared D. C. Linehan· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. C. Chacon

Mutual co-authors in cluster

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2 papers

Recent·Most cited

pan-MHC and cross-Species Prediction of T Cell Receptor-Antigen Binding

Y. Han, Y. Yang, Y. Tian, F. J. Fattah, M. S. v. Itzstein, M. Zhang, X. Kang, D. M. Yang, J. Liu, Y. Xue, C. Liang, I. Raman, C. Zhu, O. Xiao, Y. Hu, , T. Wang

This paper develops pMTnet-omni, an AI system predicting TCR-pMHC binding across species and MHC classes, achieving high accuracy and showing clinical utility in predicting immune-related adverse events.

bioRxiv · Dec 1, 2023 · PreprintImmunology

Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model

S. S. Qin, B. J. Han, A. Williams, K. M. Jackson, R. Jewell, A. C. Chacon, E. M. Lord, D. C. Linehan, M. Kim, A. Reuben, S. A. A. Gerber, P. A. Prieto

This study develops a murine model of synchronous melanoma to show that genetic differences between tumors create distinct immune microenvironments affecting immunotherapy response.

bioRxiv · Aug 18, 2020Cancer Biology