Author

A. Roesen-Wolff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

H. Luksch· 2 shared A. Ablasser· 1 shared A. Gerbaulet· 1 shared A. Loff· 1 shared A. M. C. Boehner· 1 shared A. Roers· 1 shared B. Hiller· 1 shared C. C. de Oliveira Mann· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

H. Luksch

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Clearance of genome-damaged cells from the hematopoietic system via p53 without contribution by the cGAS/STING axis

N. Dressel, L. Natusch, C. Munz, S. Costas-Ramon, M. N. F. Morcos, A. Loff, B. Hiller, H. Luksch, A. Roesen-Wolff, A. Roers, R. Behrendt, A. Gerbaulet

This study shows that p53 clears genome-damaged hematopoietic cells without needing the cGAS/STING pathway, and that cGAS/STING is not required for coping with DNA damage or preventing leukemia in RER-deficient conditions.

bioRxiv · Jun 24, 2022 · PreprintCell Biology

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N. Kessler, S. F. Viehmann, C. Krollmann, K. Mai, K. M. Kirschner, H. Luksch, P. Kotagiri, A. M. C. Boehner, D. Huugen, C. C. de Oliveira Mann, S. Otten, S. A. I. Weiss, T. Zillinger, K. Dobrikova, D. E. Jenne, , N. Garbi

This study identifies cGAS/STING/IFN-mediated nucleic acid sensing by monocyte-derived macrophages as a driver of severe pulmonary vasculitis and shows that targeting this pathway reduces disease severity.

bioRxiv · May 30, 2022Immunology