Author

A. Rongvaux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Bagale· 1 shared A. C. Knudsen· 1 shared A. G. Chapuis· 1 shared A. Taylor· 1 shared D. Kuppers· 1 shared D. R. Byrd· 1 shared D. S. Hunter· 1 shared E. M. Bruscia· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Bagale

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice

D. Kuppers, J. Linton, S. Ortiz, K. McKenna, A. Rongvaux, P. PADDISON

The paper develops a method to efficiently edit human CD34+ HSPCs before transplantation, enabling gene knock-outs in the human immune system of mice with high efficiency and without affecting engraftment potential.

bioRxiv · Oct 6, 2022Bioengineering

Pro-apoptotic caspase deficiency reveals a cell-extrinsic mechanism of NK cell regulation

T. M. Olsen, W. H. Tan, A. C. Knudsen, A. Rongvaux

This study shows that caspase deficiency reduces NK cell numbers and function through a cell-extrinsic mechanism involving mitochondrial DNA leakage and type I IFN response.

bioRxiv · Sep 9, 2021 · PreprintImmunology

A faithful in vivo model of human macrophages in metastatic melanoma

V. Voillet, T. R. Berger, K. M. McKenna, K. G. Paulson, K. S. Smythe, D. S. Hunter, W. J. Valente, S. J. Weaver, J. S. Campbell, T. S. Kim, D. R. Byrd, J. H. Bielas, R. H. Pierce, A. G. Chapuis, R. Gottardo, A. Rongvaux

The paper develops a humanized mouse model of metastatic melanoma that supports tumor spread and recapitulates patient macrophage transcriptomes, linking them to poor survival.

bioRxiv · Sep 9, 2021 · PreprintImmunology

A Highly Efficient and Faithful MDS Patient-Derived Xenotransplantation Model for Pre-Clinical Studies

Y. Song, A. Rongvaux, A. Taylor, T. Jiang, T. Tebaldi, K. Balasubramanian, A. Bagale, Y. K. Terzi, R. Gbyli, X. Wang, J. Zhao, N. Podoltsev, M. Xu, N. Neparidze, E. Wong, , S. Halene

This paper develops a novel MDS patient-derived xenotransplantation model in MISTRG mice that faithfully represents all MDS subtypes and enables effective drug testing.

bioRxiv · Feb 14, 2018Cancer Biology