Author

S. J. Weaver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. J. Jensen· 2 shared A. B. Dalia· 1 shared A. G. Chapuis· 1 shared A. Rongvaux· 1 shared A. Shiriaeva· 1 shared D. R. Byrd· 1 shared D. S. Hunter· 1 shared J. H. Bielas· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

G. J. Jensen

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Author profile →

4 papers

Recent·Most cited

A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals

M. W. Martynowycz, A. Shiriaeva, M. T. B. Clabbers, W. J. Nicolas, S. J. Weaver, J. Hattne, T. Gonen

This paper introduces a method to prepare lipidic cubic phase (LCP) membrane protein crystals for MicroED by using fluorescence microscopy to identify and mill crystals without converting LCP to sponge phase.

bioRxiv · Jul 26, 2022Biochemistry

A faithful in vivo model of human macrophages in metastatic melanoma

V. Voillet, T. R. Berger, K. M. McKenna, K. G. Paulson, K. S. Smythe, D. S. Hunter, W. J. Valente, S. J. Weaver, J. S. Campbell, T. S. Kim, D. R. Byrd, J. H. Bielas, R. H. Pierce, A. G. Chapuis, R. Gottardo, A. Rongvaux

The paper develops a humanized mouse model of metastatic melanoma that supports tumor spread and recapitulates patient macrophage transcriptomes, linking them to poor survival.

bioRxiv · Sep 9, 2021 · PreprintImmunology

CryoEM structure of the Vibrio cholerae Type IV competence pilus secretin PilQ

S. J. Weaver, M. H. Sazinsky, T. N. Dalia, A. B. Dalia, G. J. Jensen

The paper determines the cryoEM structure of V. cholerae PilQ, revealing its architecture and function in DNA transfer, and identifies it as a potential drug target.

bioRxiv · Mar 3, 2020Biophysics

Fusion of DARPin to aldolase enables visualization of small protein by cryoEM

Q. Yao, S. J. Weaver, J.-Y. Mock, G. J. Jensen

The paper describes a platform using DARPin fused to aldolase to visualize small proteins by cryoEM, achieving 5-8 Å resolution for GFP.

bioRxiv · Oct 30, 2018Biophysics