Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
K. V. Sukhoverkov, A. S. B. Jalal, D. M. Lawson, T. B. K. Le
The paper solves the structure of a truncated Bacillus subtilis Noc protein bound to NBS DNA, revealing disengagement between its CTP-binding and DNA-binding domains.
A. S. B. Jalal, N. T. Tran, C. E. M. Stevenson…·T. B. K. Le
This study identifies a CTP-dependent gating mechanism in ParB that regulates its nucleation, spreading, and recycling during chromosome segregation in Caulobacter crescentus.
A. S. B. Jalal, N. T. Tran, L. J. Wu…·T. B. K. Le
This study shows that CTP regulates the membrane-binding activity of the nucleoid occlusion protein Noc in Bacillus subtilis by controlling its ability to form nucleoprotein complexes.
A. S. B. Jalal, N. T. Tran, C. E. Stevenson…·T. B. K. Le
This study investigates how DNA-binding specificity diversifies in ParB and Noc proteins by identifying key residues and mutational paths that reprogram specificity.
A. S. B. Jalal, N. T. Tran, T. B. K. Le
This study shows that cytidine triphosphate (CTP) is required for ParB spreading on DNA in vitro, using purified proteins from Caulobacter crescentus.
N. T. Tran, C. E. Stevenson, N. F. Som…·T. B. K. Le
The paper identifies additional parS sites and characterizes ParB's genomic distribution in Caulobacter crescentus, showing its role in chromosome segregation.