Author

A. Saini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Banerjee· 2 shared R. Prasad· 2 shared A. Chakrabarti· 1 shared A. Chauhan· 1 shared A. E. Medlock· 1 shared A. K. Mondal· 1 shared A. M. Lynn· 1 shared A. Narayanan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

A. Banerjee

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Microevolution of clade II isolates of Candida auris highlights multifaceted intra-clade heterogeneity in acquiring resistance towards amphotericin B

A. Chauhan, P. Kumar, M. Kumar, A. Narayanan, K. Yadav, B. Ali, A. Saini, A. Singh, A. Banerjee, S. M. Rudramurthy, A. Chakrabarti, A. K. Mondal, N. A. Gaur, K. Sanyal, R. Prasad

This study evolves two clade II Candida auris isolates to develop amphotericin B resistance, revealing distinct mechanisms and intra-clade heterogeneity in resistance acquisition.

bioRxiv · Sep 20, 2023 · PreprintMicrobiology

Genomic landscape of the DHA1 family in the newly emerged pathogen Candida auris and mapping substrate repertoire of the prominent member CauMdr1

R. Khatoon, S. Sharma, P. Vishwakarma, A. Saini, P. Aggarwal, A. M. Lynn, A. Prakash, R. Prasad, A. Banerjee

This study maps the DHA1 family in Candida auris and identifies substrates of CauMdr1, showing overexpression increases antifungal resistance.

bioRxiv · Mar 9, 2022 · PreprintMicrobiology

Genome-wide Analysis of Bromodomain Gene Family in Arabidopsis and Rice

A. T. V., R. P. Sanyal, H. S. Misra, A. Saini

This study analyzes the bromodomain gene family in Arabidopsis and rice, revealing structural diversity, genomic duplication, alternative splicing, and functional implications across species.

bioRxiv · Feb 8, 2022Plant Biology

Epigenetic Instability May Alter Cell State Transitions and Anticancer Drug Resistance

A. Saini, J. M. Gallo

This study develops stochastic cell state models to show that epigenetic instability reduces drug-resistant cell populations by up to 90% in brain tumors.

bioRxiv · Nov 15, 2020Cancer Biology

The heme biosynthetic enzyme, 5-aminolevulinic acid synthase (ALAS), and GTPases in control of mitochondrial dynamics and ER contact sites, regulate heme mobilization to the nucleus.

O. Martinez-Guzman, M. M. Willoughby, A. Saini, J. V. Dietz, I. Bohovych, A. E. Medlock, O. Khalimonchuk, A. R. Reddi

The paper develops a live-cell assay to study heme trafficking and identifies ALAS and GTPases as regulators of heme mobilization from mitochondria to the nucleus.

bioRxiv · Aug 13, 2019 · PreprintCell Biology