Author

A. Santoni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Folgori· 2 shared A. Natalini· 2 shared A. Nicosia· 2 shared F. Di Rosa· 2 shared S. Capone· 2 shared S. Simonetti· 2 shared A. C. Hayday· 1 shared A. M. Contino· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

A. Folgori

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Targeting DNA2 Overcomes Metabolic Reprogramming in Multiple Myeloma

N. Thongon, F. Ma, P. Lockyer, N. Baran, J. Liu, C. Jackson, A. Rose, B. Wildeman, M. Marchesini, V. Marchica, P. Storti, N. Giuliani, I. Ganan-Gomez, V. Adema, Y. Qing, , S. Colla

This study identifies DNA2 as a key factor in mitochondrial metabolism that enables multiple myeloma cells to survive DNA damage, showing that targeting DNA2 overcomes metabolic reprogramming and enhances therapy effectiveness.

bioRxiv · Feb 22, 2023Cancer Biology

Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature.

A. Natalini, S. Simonetti, G. Favaretto, L. Lucantonio, G. Peruzzi, M. Munoz-Ruiz, G. Kelly, A. M. Contino, R. Sbrocchi, S. Battella, S. Capone, A. Folgori, A. Nicosia, A. Santoni, A. C. Hayday, F. Di Rosa

The study shows that a delayed vaccine boost at day 100 post-prime enhances CD8 T cell memory response compared to day 30, with a distinct molecular signature in splenic cells.

bioRxiv · Aug 4, 2022Immunology

When killers become thieves: trogocytosed PD-1 inhibits NK cells in cancer

M. S. Hasim, M. Marotel, J. J. Hodgins, E. Vulpis, H.-Y. Shih, A. Scheer, O. MacMillan, F. Alonso, K. Burke, D. P. Cook, M. T. Petrucci, A. Santoni, P. Fallon, A. Sharpe, G. Sciume, , M. Ardolino

Natural Killer cells acquire PD-1 from tumor cells via trogocytosis, which inhibits anti-tumor immunity.

bioRxiv · Jun 26, 2020Immunology

A previously missed population of antigen-specific CD8 T cells divides in the blood after vaccination

S. Simonetti, A. Natalini, A. Folgori, S. Capone, A. Nicosia, A. Santoni, F. Di Rosa

bioRxiv · Aug 14, 2018Immunology