Author

B. Yuksel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:protein structure· 3 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Ayan· 4 shared E. Destan· 4 shared H. DeMirci· 4 shared C. Dag· 3 shared C. H. Yoon· 3 shared F. B. Ertem· 3 shared G. Yildirim· 3 shared M. Liang· 3 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBiophysics

E. Ayan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural Analysis of Wild-type and Val120Thr Mutant Candida boidinii Formate Dehydrogenase by X-ray Crystallography

M. Gul, B. Yuksel, H. Bulut, H. DeMirci

This study reports X-ray crystal structures of wild-type and Val120Thr mutant CbFDH, revealing structural changes that may enhance enzyme stability and electron transfer efficiency.

bioRxiv · Dec 25, 2022 · PreprintBiophysics

Cooperative Allostery and Structural Dynamics of Streptavidin at Cryogenic- and Ambient-temperature

E. Ayan, B. Yuksel, E. Destan, F. B. Ertem, G. Yildirim, M. Eren, O. M. Yefanov, A. Barty, A. Tolstikova, G. K. Ketawala, S. Botha, E. H. Dao, B. Hayes, M. Liang, M. H. Seaberg, , H. DeMirci

The paper presents two apo-streptavidin structures at different temperatures and reveals cooperative allostery through water-mediated interactions.

bioRxiv · Sep 23, 2021Biophysics

Structural Insights into Bifunctional Thaumarchaeal Crotonyl-CoA Hydratase and 3-Hydroxypropionyl-CoA Dehydratase from Nitrosopumilus maritimus

E. Destan, B. Yuksel, B. B. Tolar, E. Ayan, S. Deutsch, Y. Yoshikuni, S. Wakatsuki, C. A. Francis, H. DeMirci

This study presents the first high-resolution crystal structure of a bifunctional enzyme involved in the 3HP/4HB cycle in Nitrosopumilus maritimus, revealing its dual catalytic activities.

bioRxiv · Sep 22, 2021 · PreprintBiochemistry

Structural insight into host plasma membrane association and assembly of HIV-1 Matrix protein

H. Ciftci, H. Tateishi, K. Koiwai, R. Koga, K. Anraku, K. Monde, C. Dag, E. Destan, B. Yuksel, E. Ayan, G. Yildirim, M. Yigin, F. B. Ertem, A. Shafiei, O. Guven, , H. DeMirci

This study presents crystal structures of HIV-1 MA domain bound to IP6, revealing its binding mode and interaction with PIP2, providing insights into virion assembly.

bioRxiv · Feb 21, 2021 · PreprintMicrobiology

Near-Physiological-Temperature Serial Femtosecond X-ray Crystallography Reveals Novel Conformations of SARS-CoV-2 Main Protease Active Site for Improved Drug Repurposing

S. Durdagi, C. Dag, B. Dogan, M. Yigin, T. Avsar, C. Buyukdag, I. Erol, F. B. Ertem, S. Calis, G. Yildirim, M. Orhan, O. Guven, B. Aksoydan, E. Destan, K. Sahin, , Sn

The paper determines two apo structures of SARS-CoV-2 main protease at near-physiological temperature using SFX and uses molecular simulations to analyze inhibitor binding for drug repurposing.

bioRxiv · Sep 9, 2020Biophysics