HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation
S. Scinicariello, A. Soederholm, M. Schaefer, A. Shulkina, I. Schwartz, K. Hacker, R. Gogova, R. Kalis, K. Froussios, V. Budroni, A. Bestehorn, T. Clausen, P. Kovarik, J. Zuber, G. A. Versteeg
This study identifies HUWE1 as a regulator of TTP proteasomal degradation by controlling its phosphorylation, distinct from MAPK-mediated phosphorylation.
bioRxiv · Aug 29, 2022Cell Biology