Author

P. Kovarik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bestehorn· 2 shared A. Drobek· 1 shared A. Hagelkrueys· 1 shared A. Kavirayani· 1 shared A. Shulkina· 1 shared A. Soederholm· 1 shared C. Gomez Diaz· 1 shared D. Glatzova· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

A. Bestehorn

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation

S. Scinicariello, A. Soederholm, M. Schaefer, A. Shulkina, I. Schwartz, K. Hacker, R. Gogova, R. Kalis, K. Froussios, V. Budroni, A. Bestehorn, T. Clausen, P. Kovarik, J. Zuber, G. A. Versteeg

This study identifies HUWE1 as a regulator of TTP proteasomal degradation by controlling its phosphorylation, distinct from MAPK-mediated phosphorylation.

bioRxiv · Aug 29, 2022Cell Biology

The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains

C. Gomez Diaz, G. Jonsson, K. Schodl, L. Deszcz, A. Bestehorn, K. Eislmayr, J. Almagro, A. Kavirayani, L. M. Fennell, A. Hagelkrueys, P. Kovarik, J. M. Penninger, F. Ikeda

This study shows that the HOIL-1L NZF domain regulates immune responses by binding linear ubiquitin chains, affecting TNF and LPS-induced inflammation in mice.

bioRxiv · Apr 13, 2021Cell Biology

Regulation of neutrophil NADPH oxidase by PSTPIP2 affects bone damage in murine autoinflammatory osteomyelitis

J. Kralova, A. Drobek, J. Prochazka, F. Spoutil, D. Glatzova, S. Borna, J. Pokorna, T. Skopcova, P. Angelisova, M. Gregor, P. Kovarik, R. Sedlacek, T. Brdicka

This study shows that PSTPIP2 regulates neutrophil NADPH oxidase, and its loss leads to increased ROS production and bone damage in a murine model of autoinflammatory osteomyelitis.

bioRxiv · Aug 6, 2019 · PreprintImmunology