Author

A. T. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Y.-Y. Liu· 2 shared A. F. Yu· 1 shared A. Greenhough· 1 shared A. Gsur· 1 shared A. M. Schmitt· 1 shared A. Nounu· 1 shared A. Piersigilli· 1 shared A. Shamseddine· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

Y.-Y. Liu

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Author profile →

4 papers

Recent·Most cited

Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments

T. Wang, Y. Fu, M. Shuai, J.-S. Zheng, L. Zhu, A. T. Chan, Q. Sun, F. B. Hu, S. T. Weiss, Y.-Y. Liu

This study introduces METRIC, a deep-learning method that uses gut microbiome data to correct random errors in self-reported dietary assessments, showing effectiveness in simulated and real-world datasets.

bioRxiv · Nov 21, 2023Microbiology

Innate immune signaling drives late cardiac toxicity following DNA damaging cancer therapies

A. Shamseddine, S. Patel, V. Chavez, M. Adnan, M. Di Bona, J. Li, C. T. Dang, L. V. Ramanathan, K. C. Oeffinger, J. E. Liu, R. M. Steingart, A. Piersigilli, N. D. Socci, A. T. Chan, A. F. Yu, , A. M. Schmitt

This study identifies cGAS-STING signaling as a driver of late cardiac toxicity after DNA-damaging cancer therapies and shows that targeting this pathway can mitigate cardiotoxicity.

Journal of Experimental Medicine · Dec 19, 2022Peer-reviewedImmunology

Gut feelings: Associations of emotions and emotion regulation with the gut microbiome in women

S. Ke, A.-J. Guimond, S. Tworoger, T. Huang, A. T. Chan, Y.-Y. Liu, L. D. Kubzansky

This study investigates associations between emotions, emotion regulation, and the gut microbiome in women, finding links between emotional states and microbial diversity and pathways.

bioRxiv · May 26, 2022Microbiology

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

A. Nounu, A. Greenhough, K. J. Heesom, R. C. Richmond, J. Zheng, S. J. Weinstein, D. Albanes, J. A. Baron, J. L. Hopper, J. C. Figueiredo, P. A. Newcomb, N. M. Lindor, G. Casey, E. A. Platz, L. Le Marchand, , G. Rennert

This study combines proteomics and Mendelian randomization to identify aspirin-targeted proteins associated with reduced colorectal cancer risk.

bioRxiv · Aug 14, 2020Cancer Biology