Author

N. D. Socci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. F. Yu· 1 shared A. Hayashi· 1 shared A. M. Schmitt· 1 shared A. P. Makohon-Moore· 1 shared A. Piersigilli· 1 shared A. Shamseddine· 1 shared A. T. Chan· 1 shared A. Zucker· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. F. Yu

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Author profile →

2 papers

Recent·Most cited

Innate immune signaling drives late cardiac toxicity following DNA damaging cancer therapies

A. Shamseddine, S. Patel, V. Chavez, M. Adnan, M. Di Bona, J. Li, C. T. Dang, L. V. Ramanathan, K. C. Oeffinger, J. E. Liu, R. M. Steingart, A. Piersigilli, N. D. Socci, A. T. Chan, A. F. Yu, , A. M. Schmitt

This study identifies cGAS-STING signaling as a driver of late cardiac toxicity after DNA-damaging cancer therapies and shows that targeting this pathway can mitigate cardiotoxicity.

Journal of Experimental Medicine · Dec 19, 2022Peer-reviewedImmunology

Evolutionary Dynamics of Non-Coding Regions in Pancreatic Ductal Adenocarcinoma

A. Hayashi, Y.-j. Ho, A. P. Makohon-Moore, A. Zucker, J. Hong, J. G. Reiter, J. Huang, L. Zhang, M. A. Attiyeh, P. Baez, R. Kappagantula, J. P. Melchor, E. M. OReilly, N. D. Socci, S. Oki, , C. A. Iacobuzio-Donahue

This study investigates the evolutionary dynamics of non-coding regions in pancreatic cancer, finding higher mutational burden in noncoding DNA and similar mutational spectra between enhancers and coding DNA.

bioRxiv · Sep 11, 2020 · PreprintCancer Biology