A. Tata

Novel porcine model reveals two distinct LGR5 cell types during lung development and homeostasis

The paper identifies two distinct LGR5+ cell types in the lung using a novel porcine model, showing conservation in humans but not mice.

Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

The paper shows that ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells, contributing to maladaptive renal repair after severe injury.

The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro

This study identifies Alectinib as an FDA-approved drug that inhibits SARS-CoV-2 nucleocapsid phosphorylation and viral replication in vitro by targeting host kinases.

A dendritic-like microtubule network is organized from swellings of the basal fiber in neural progenitors

The paper shows that microtubules in the basal fiber of radial glial cells form a dendritic-like network through acentrosomal organizing centers, conserved in human fetal cortex.

The metronomic combination of paclitaxel with cholinergic agonists inhibits triple negative breast tumor progression. Participation of M2 receptor subtype

The paper investigates the effect of combining paclitaxel with muscarinic agonists on triple negative breast tumors, finding that M2 receptor activation reduces cell viability and tumor progression.

Persistence of a novel regeneration-associated transitional cell state in pulmonary fibrosis

The paper identifies a novel transitional cell state in lung regeneration that exhibits senescence-like features and is enriched in fibrotic lung tissues, suggesting its role in pulmonary fibrosis pathogenesis.