P. R. Tata

Allergic Asthma Responses Are Dependent on Macrophage Ontogeny

This study shows that altering macrophage ontogeny after homeostasis affects allergic airway responses to house dust mites.

Novel porcine model reveals two distinct LGR5 cell types during lung development and homeostasis

The paper identifies two distinct LGR5+ cell types in the lung using a novel porcine model, showing conservation in humans but not mice.

Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

The paper shows that ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells, contributing to maladaptive renal repair after severe injury.

The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro

This study identifies Alectinib as an FDA-approved drug that inhibits SARS-CoV-2 nucleocapsid phosphorylation and viral replication in vitro by targeting host kinases.

A Versatile Oblique Plane Microscope for Large-Scale and High-Resolution Imaging of Subcellular Dynamics.

This paper introduces an improved oblique plane microscope with enhanced resolution and usability, demonstrating its application in imaging various subcellular dynamics and challenging biological phenomena.

Persistence of a novel regeneration-associated transitional cell state in pulmonary fibrosis

The paper identifies a novel transitional cell state in lung regeneration that exhibits senescence-like features and is enriched in fibrotic lung tissues, suggesting its role in pulmonary fibrosis pathogenesis.