Author

A. Thawani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Organism:Xenopus· 3 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

S. Petry· 3 shared H. A. Stone· 2 shared J. W. Shaevitz· 2 shared A. Yildiz· 1 shared E. Nogales· 1 shared G. Bhabha· 1 shared J. M. Perez-Bertoldi· 1 shared M. J. Rale· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

S. Petry

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular interplay between HURP and Kif18A in mitotic spindle regulation

J. M. Perez-Bertoldi, Y. Zhao, A. Thawani, A. Yildiz, E. Nogales

This study investigates how HURP regulates Kif18A motility and microtubule dynamics during mitosis using single-molecule imaging and Cryo-EM.

bioRxiv · Apr 11, 2024 · PreprintBiophysics

The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy

A. Thawani, M. J. Rale, N. Coudray, G. Bhabha, H. A. Stone, J. W. Shaevitz, S. Petry

This study uses single molecule microscopy to reveal how γ-TuRC nucleates microtubules, showing a cooperative mechanism involving 4 β-tubulin dimers and the role of XMAP215 in enhancing nucleation efficiency.

bioRxiv · Jun 13, 2020Cell Biology

Biochemical reconstitution of branching microtubule nucleation

R. Alfaro-Aco, A. Thawani, S. Petry

This study reconstitutes branching microtubule nucleation using purified Xenopus proteins, identifying augmin and TPX2 as essential factors that guide gamma-TuRC to nucleate branched microtubules.

bioRxiv · Jul 11, 2019Cell Biology

Spatiotemporal organization of branched microtubule networks

A. Thawani, H. A. Stone, J. W. Shaevitz, S. Petry

The paper studies branched microtubule network formation in Xenopus egg extracts, showing that TPX2, augmin, and γ-TuRC regulate nucleation through a sequential reaction pathway.

bioRxiv · Apr 12, 2019Biophysics